0369540 20240103200055.220120120235959.9 6 s. cav_un_epca*0371893978-0-415-68395-11-6LondonTaylor and Francis2011ManuelJ.TavaresR. S.JorgeN. positron emission tomography Monte Carlo simulation biological system modeling image quality cav_un_auth*0101071 Boldyš Jiří Zpracování obrazové informace Department of Image Processing ZOI ZOI UTIA-B Department of Image Processing Ústav teorie informace a automatizace AV ČR, v. v. i. cav_un_auth*0273046 Dvořák Jiří Zpracování obrazové informace Department of Image Processing ZOI ZOI UTIA-B Department of Image Processing Ústav teorie informace a automatizace AV ČR, v. v. i. cav_un_auth*0214731 Bělohlávek O. CZ cav_un_auth*0278597 Skopalová M. CZ http://library.utia.cas.cz/separaty/2012/ZOI/boldys-monte carlo simulation of pet images for injection dose optimization.pdf 1M0572 GA MŠk CZ cav_un_auth*0001814 CEZ:AV0Z10750506 When a patient is examined by positron emission tomography, radiotracer dose amount has to be determined. However, the rules used nowadays do not correspond with practical experience. Slim patients are given unnecessary amount of radiotracer and obese patients would need more activity to produce images of sufficient quality. We have built a model of a particular PET scanner and approximated human trunk, which is our region of interest, by a cylindrical model with segments of liver, outer adipose tissue and the rest. We have performed Monte Carlo simulations of PET imaging using the GATE simulation package. Under reasonably simplifying assumptions and for special parameters, we have developed curves, which recommend amount of injected activity based on body parameters to give PET images of constant quality. The dependence qualitatively differs from the rules used in clinical practice nowadays and the results indicate potential for improvement cav_un_auth*0277448 VipIMAGE 2011 - third ECCOMAS thematic conference on computational vision and medical image processing Olhao, Algarve 12.10.2011-14.10.2011 PT 2012 BD 4 http://hdl.handle.net/11104/0203576 2011 cav_un_epca*0371893 Computational Vision and Medical Image Processing: VipIMAGE 2011 978-0-415-68395-1 1 6 London Taylor and Francis 2011 Manuel J. 340 Tavares R. S. 340 Jorge N. 340