0432206 20240111140851.620141017235959.9 10.1007/978-3-319-10759-2_29 10 s. P cav_un_epca*0432198978-3-319-10758-52194-7287Part III277-286ChamSpringer2014SanayeiA.RosslerE. O.ZelinkaI. Microalgae photobioreactor optimization multiscale modeling flashing light effect cav_un_auth*0014364 Papáček Š. CZ cav_un_auth*0314067 Jablonský J. CZ cav_un_auth*0016460 Petera K. CZ cav_un_auth*0216347 Rehák Branislav Teorie řízení Department of Control Theory TŘ TR UTIA-B Department of Control Theory Ústav teorie informace a automatizace AV ČR, v. v. i. cav_un_auth*0100790 Matonoha Ctirad Oddělení optimalizace a systémů Department of Optimization and Systems UIVT-O Department of Computational Mathematics Ústav informatiky AV ČR, v. v. i. textový dokument 733 kB Microalgae have the potential to be a major biofuel source in the future. Computational biology plays a key role in understanding biological processes within microalgae and optimizing biofuel production. Here, we present a multidisciplinary, multi-timescale modeling approach of microalgae growth in photobioreactors. Our modeling framework bridges biology (cell growth), physics (hydrodynamics and light distribution), and optimization together. This framework consists of (i) the state system (mass balance equations in form of advectiondiffusion- reaction PDEs), (ii) the fluid flow equations (the Navier-Stokes equations), and (iii) the optimization problem formulation. The modeling and optimization of microalgae growth in a Couette-Taylor reactor is presented to demonstrate this method. We show how the flashing light effect can be an intrinsic part of the model. Finally, we discuss further methodological integration with the metabolomic-transcriptomic kinetic model, which explains cellular concentrations of key metabolites in connection with cell growth. cav_un_auth*0307020 ISCS 2014: The Interdisciplinary Symposium on Complex Systems Florencie 15.09.2014-18.09.2014 IT 2015 BC 5 4 O 4o 20231122140445.3 PR UIVT-O BA RVO:67985556 RVO:67985807 http://hdl.handle.net/11104/0236720 cav_un_auth*0307027 University of South Bohemia in Ceske Budejovice, FFPW USB, CENAKVA, Institute of Complex Systems CZ S 2014 Soubory v repozitáři: 0432206.pdf textový dokument 733 kB cav_un_epca*0432198 ISCS 2014: Interdisciplinary Symposium on Complex Systems Part III 978-3-319-10758-5 2194-7287 277 286 Cham Springer 2014 Library of Congress Control Number: 2014949171 Emergence, Complexity and Computation ECC 14 Sanayei A. 340 Rossler E. O. 340 Zelinka I. 340