0474149 20240103214011.720170425235959.9 85013212220 000397963400013 10.1016/j.clinph.2016.12.027 13 s. cav_un_epca*02554981388-24571284 (2017)622-634Elsevier physiological tremor essential tremor bilateral coupling coherence ballistocardiac impulse accelerometry wavelet analysis cav_un_auth*0320789 Chakraborty Soma Početní neurovědy Computational Neuroscience FGU-C Laboratory of Computational Neuroscience Fyziologický ústav AV ČR, v. v. i. cav_un_auth*0251769 Kopecká J. CZ cav_un_auth*0228408 Šprdlík Otakar Teorie řízení Department of Control Theory TŘ TR UTIA-B CZ Ústav teorie informace a automatizace AV ČR, v. v. i. cav_un_auth*0255917 Hoskovcová M. CZ cav_un_auth*0271852 Ulmanová O. CZ cav_un_auth*0040406 Růžička E. CZ cav_un_auth*0259752 Zápotocký Martin Početní neurovědy Computational Neuroscience FGU-C Laboratory of Computational Neuroscience K Fyziologický ústav AV ČR, v. v. i. cav_un_auth*0282945 GBP304/12/G069 GA ČR CZ We investigated the prevalence and the temporal structure of bilateral coherence in physiological (PT) and essential (ET) hand tremor. Triaxial accelerometric recordings from both hands in 30 healthy subjects and 34 ET patients were analyzed using spectral coherence and wavelet coherence methods. In 12 additional healthy subjects, the relation between the hand tremor and the chest wall acceleration was evaluated using partial coherence analysis. The majority of both PT and ET subjects displayed significant bilateral coherence. While in PT, bilateral coherence was most frequently found in resting hand position (97% of subjects), in ET the prevalence was comparable for resting (54%) and postural (49%–57%) positions. In both PT and ET, epochs of strong coherence lasting several to a dozen seconds were separated by intervals of insignificant coherence. In PT, bilateral coherence at the main tremor frequency (8–12 Hz) was coupled with the ballistocardiac rhythm. The oscillations of the two hands are intermittently synchronized in both PT and ET. We propose that in postural PT, bilateral coherence at the main tremor frequency arises from transient simultaneous entrainment of the left and right hand oscillations to ballistocardiac forcing. Bilateral coherence of hand kinematics provides a sensitive measure of synchronizing influences on the left and right tremor oscillators. FH 30000 30100 30103 2018 UTIA-B 10000 10200 10201 UTIA-B BC RVO:67985823 RVO:67985556 http://hdl.handle.net/11104/0271260 cav_un_auth*0307941 Univerzita Karlova v Praze, 1. lékařská fakulta 1. LF UK CZ S 3+4 Article Clinical Neurology|Neurosciences 3+4 Article Clinical Neurology|Neurosciences 3+4 Article Clinical Neurology|Neurosciences CLINICALNEUROLOGY|NEUROSCIENCES 3.638 0.992 9.5 0.02305 1.142 18399 1.561 3.242 265 Q2 56.383 70.5 Q2 Q2 1.14 Q1 73.35 2017 85013212220 SCOPUS 28231479 PUBMED 000397963400013 WOS cav_un_epca*0255498 Clinical Neurophysiology 1388-2457 1872-8952 Roč. 128 č. 4 2017 622 634 Elsevier