bibtype J - Journal Article
ARLID 0431811
utime 20240103204633.0
mtime 20150212235959.9
WOS 000335422800015
SCOPUS 84899052979
DOI 10.1016/j.mri.2014.02.003
title (primary) (eng) The precision of DCE-MRI using the tissue homogeneity model with continuous formulation of the perfusion parameters
specification
page_count 9 s.
media_type P
serial
ARLID cav_un_epca*0254220
ISSN 0730-725X
title Magnetic Resonance Imaging
volume_id 32
volume 5 (2014)
page_num 505-513
publisher
name Elsevier
keyword dynamic contrast-enhanced MRI (DCE-MRI)
keyword perfusion
keyword parameter estimation
keyword bolus arrival time
author (primary)
ARLID cav_un_auth*0312355
name1 Bartoš
name2 Michal
full_dept (cz) Zpracování obrazové informace
full_dept (eng) Department of Image Processing
department (cz) ZOI
department (eng) ZOI
institution UTIA-B
full_dept Department of Image Processing
fullinstit Ústav teorie informace a automatizace AV ČR, v. v. i.
author
ARLID cav_un_auth*0277120
name1 Jiřík
name2 Radovan
full_dept (cz) D3: Magnetická rezonance a Kryogenika
full_dept D3: Magnetic Resonance and Cryogenics
institution UPT-D
full_dept Magnetic Resonance and Cryogenics
fullinstit Ústav přístrojové techniky AV ČR, v. v. i.
author
ARLID cav_un_auth*0306308
name1 Kratochvíla
name2 Jiří
full_dept (cz) D3: Magnetická rezonance a Kryogenika
full_dept D3: Magnetic Resonance and Cryogenics
institution UPT-D
full_dept Magnetic Resonance and Cryogenics
fullinstit Ústav přístrojové techniky AV ČR, v. v. i.
author
ARLID cav_un_auth*0278224
name1 Standara
name2 M.
country CZ
author
ARLID cav_un_auth*0101622
name1 Starčuk jr.
name2 Zenon
full_dept (cz) D3: Magnetická rezonance a Kryogenika
full_dept D3: Magnetic Resonance and Cryogenics
institution UPT-D
full_dept Magnetic Resonance and Cryogenics
fullinstit Ústav přístrojové techniky AV ČR, v. v. i.
author
ARLID cav_un_auth*0306309
name1 Torfinn
name2 T.
country NO
cas_special
project
project_id GAP102/12/2380
agency GA ČR
ARLID cav_un_auth*0285036
project
project_id ED0017/01/01
agency GA MŠk
ARLID cav_un_auth*0266369
project
project_id LO1212
agency GA MŠk
country CZ
ARLID cav_un_auth*0303710
abstract (eng) The present trend in dynamic contrast-enhanced MRI is to increase the number of estimated perfusion parameters using complex pharmacokinetic models. However, less attention is given to the precision analysis of the parameter estimates. In this paper, the distributed capillary adiabatic tissue homogeneity pharmacokinetic model is extended by the bolus arrival time formulated as a free continuous parameter. With the continuous formulation of all perfusion parameters, it is possible to use standard gradient-based optimization algorithms in the approximation of the-tissue concentration time sequences. This new six-parameter model is investigated by comparing Monte-Carlo simulations with theoretically derived covariance matrices. The covariance-matrix approach is extended from the usual analysis of the primary perfusion parameters of the pharmacokinetic model to the analysis of the perfusion parameters derived from the primary ones. The results indicate that the precision of the estimated perfusion parameters can be described by the covariance matrix for signal-to-noise ratio higher than similar to 20 dB. The application of the new analysis model on a real DCE-MRI data set is also presented.
reportyear 2015
RIV FS
num_of_auth 6
mrcbC52 4 A 4a 20231122140431.2
inst_support RVO:67985556
inst_support RVO:68081731
permalink http://hdl.handle.net/11104/0236363
confidential S
mrcbT16-e RADIOLOGYNUCLEARMEDICINEMEDICALIMAGING
mrcbT16-j 0.795
mrcbT16-s 1.031
mrcbT16-4 Q1
mrcbT16-B 51.924
mrcbT16-C 61.200
mrcbT16-D Q2
mrcbT16-E Q2
arlyear 2014
mrcbTft \nSoubory v repozitáři: 0431811.pdf
mrcbU14 84899052979 SCOPUS
mrcbU34 000335422800015 WOS
mrcbU63 cav_un_epca*0254220 Magnetic Resonance Imaging 0730-725X 1873-5894 Roč. 32 č. 5 2014 505 513 Elsevier