| bibtype |
C -
Conference Paper (international conference)
|
| ARLID |
0538773 |
| utime |
20240111141048.2 |
| mtime |
20210128235959.9 |
| title
(primary) (eng) |
Mathematics and Optimal control theory meet Pharmacy: Towards application of special techniques in modeling, control and optimization of biochemical networks |
| specification |
| page_count |
4 s. |
| media_type |
P |
|
| serial |
| ARLID |
cav_un_epca*0538772 |
| ISBN |
978-80-86407-82-1 |
| title
|
Proceedings of the SNA'21 Seminar on Numerical Analysis Modelling and Simulation of Challenging Engineering Problems |
| page_num |
60-63 |
| publisher |
| place |
Ostrava |
| name |
Institute of Geonics of the Czech Academy of Sciences |
| year |
2021 |
|
| editor |
|
| editor |
| name1 |
Sysala |
| name2 |
Stanislav |
|
|
| keyword |
Dynamical system |
| keyword |
Systems pharmacology |
| keyword |
Biochemical network |
| keyword |
Input-output regulation |
| keyword |
Optimization |
| author
(primary) |
| ARLID |
cav_un_auth*0404313 |
| name1 |
Papáček |
| name2 |
Štěpán |
| institution |
UTIA-B |
| full_dept (cz) |
Teorie řízení |
| full_dept (eng) |
Department of Control Theory |
| department (cz) |
TŘ |
| department (eng) |
TR |
| country |
CZ |
| fullinstit |
Ústav teorie informace a automatizace AV ČR, v. v. i. |
|
| author
|
| ARLID |
cav_un_auth*0100790 |
| name1 |
Matonoha |
| name2 |
Ctirad |
| institution |
UIVT-O |
| full_dept (cz) |
Oddělení výpočetní matematiky |
| full_dept |
Department of Computational Mathematics |
| full_dept |
Department of Computational Mathematics |
| fullinstit |
Ústav informatiky AV ČR, v. v. i. |
|
| author
|
| ARLID |
cav_un_auth*0208862 |
| name1 |
Duintjer Tebbens |
| name2 |
Jurjen |
| institution |
UIVT-O |
| full_dept (cz) |
Oddělení výpočetní matematiky |
| full_dept |
Department of Computational Mathematics |
| full_dept |
Department of Computational Mathematics |
| country |
NL |
| fullinstit |
Ústav informatiky AV ČR, v. v. i. |
|
| source |
|
| cas_special |
| project |
| project_id |
GA19-05872S |
| agency |
GA ČR |
| country |
CZ |
| ARLID |
cav_un_auth*0376352 |
|
| abstract
(eng) |
Similarly to other scienti c domains, the expenses related to in silico modeling in pharmacology need not be extensively apologized. Vis a vis both in vitro and in vivo experiments, physiologically-based pharmacokinetic (PBPK) and pharmacodynamic models represent an important tool for the assessment of drug safety before its approval, as well as a viable option in designing dosing regimens. In this contribution, some special techniques related to the mathematical modeling, control and optimization of biochemical networks are presented on a paradigmatic example of enzyme kinetics. |
| action |
| ARLID |
cav_un_auth*0404315 |
| name |
SNA'21 Seminar on Numerical Analysis Modelling and Simulation of Challenging Engineering Problems (SNA'21 2021) |
| dates |
20210125 |
| mrcbC20-s |
20210129 |
| place |
Ostrava |
| country |
CZ |
|
| RIV |
BC |
| FORD0 |
20000 |
| FORD1 |
20200 |
| FORD2 |
20205 |
| reportyear |
2021 |
| num_of_auth |
3 |
| mrcbC47 |
UIVT-O 10000 10100 10101 |
| presentation_type |
PR |
| mrcbC55 |
UIVT-O BA |
| inst_support |
RVO:67985556 |
| inst_support |
RVO:67985807 |
| permalink |
http://hdl.handle.net/11104/0316506 |
| confidential |
S |
| arlyear |
2021 |
| mrcbU14 |
SCOPUS |
| mrcbU24 |
PUBMED |
| mrcbU34 |
WOS |
| mrcbU56 |
konferenční příspěvek tuzemský 2,12 MB |
| mrcbU63 |
cav_un_epca*0538772 Proceedings of the SNA'21 Seminar on Numerical Analysis Modelling and Simulation of Challenging Engineering Problems Institute of Geonics of the Czech Academy of Sciences 2021 Ostrava 60 63 978-80-86407-82-1 |
| mrcbU67 |
Starý Jiří 340 |
| mrcbU67 |
Sysala Stanislav 340 |
|